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10 mars 2010

100310[bx1]"g"のvoxel-based lesion-symptom mapping

Spearmanのgを,
241例の局所脳損傷患者さんの病巣-症状マッピングで。

100310[bx1]-1 general intelligence; WAIS; VLSM
Distributed neural system for general intelligence revealed by lesion mapping

(おーぷんあくせす)

どこかspecific brain regions に宿るわけでもなく,global brain properties でもなく,
FとPと白質連合線維にdistributed。

(とはいえFig. 3. では,left frontal pole[BA10]に
 significant effect unique to g な領域が見いだされてもいる;
 → the need for hierarchical processing control)


We used hierarchical factor analysis across multiple cognitive tasks
to derive a robust measure of g and found statistically significant
associations between g and damage to a remarkably circumscribed
albeit distributed set of regions in left frontal and right parietal cortex,
as well as white matter association tracts connecting these sectors.
These findings suggest that g reflects the ability to effectively integrate
verbal, visuospatial, working memory, and executive processes via a
circumscribed set of cortical connections.
(p. 4705)

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